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Side effects from COVID-19 vaccine: What you should expect

Data shows a high percentage of patients who received one of the three vaccines approved in the US reported pain at the injection site

FILE - A pharmacist working for the Seattle Indian Health Board holds a syringe of the Moderna COVID-19 vaccine, Monday, March 15, 2021, at a SIHB clinic in Seattle. (AP Photo/Ted S. Warren) (Ted S. Warren, Copyright 2021 The Associated Press. All rights reserved.)

JACKSONVILLE, Fla. – The Food and Drug Administration has compiled data about side effects reported among those who have received one of the three COVID-19 vaccines approved in the United States.

The data specifically addresses eight side effects: injection site pain, fatigue, headache, body/muscle aches, joint pain, nausea/vomiting, chills, and fever.

Based on the data, a high percentage of patients who received the Pfizer, Moderna or Johnson & Johnson vaccine reported pain at the injection site. Other side effects differed based on which shot the patient received.

Pfizer vaccine

Forty-seven percent of patients between the ages of 18 and 55 who received the first dose of the Pfizer vaccine reported fatigue, 42% reported headache and 21% complained of muscle pain. A smaller percentage said they experienced chills and joint pain. Eleven percent reported diarrhea as a side effect of the vaccine. Diarrhea is only mentioned as a potential side effect for patients who received the Pfizer vaccine.

A larger percentage of patients between 18 and 55 experienced side effects when they received the second dose, compared to the first dose.

Moderna vaccine

For patients between 18 and 65 years old, fewer complained about fatigue and headache than those who received the first dose of the Pfizer vaccine, but complaints about side effects were significantly higher when these patients received the second dose of the Moderna vaccine. A larger percentage of patients reported side effects from the second Moderna dose than those who received the second dose of the Pfizer vaccine.

Johnson & Johnson vaccine

This is a single-dose shot. Forty-four percent of the patients between 18 and 59 years old reported headache and fatigue after receiving the vaccine, 39% reported body/muscle aches,16% complained of nausea and 13% reported developing a fever after getting the shot.

RELATED: How to reduce potential side effects from COVID-19 vaccine

Click here to see the entire breakdown of side effects. The data does not include severe reactions. The FDA and the Centers for Disease Control and Prevention have said there have been a few severe reactions related to allergies.


About the Author
Jennifer Waugh headshot

Jennifer, who anchors The Morning Shows and is part of the I-TEAM, loves working in her hometown of Jacksonville.

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