Ryan Tannehill threw for 333 yards and two touchdowns to outduel Aaron Rodgers as the Tennessee Titans defeated the Green Bay Packers 27-17.

Randy Bullock kicked a 44-yard field goal with 4 seconds remaining and the banged-up Tennessee Titans rallied from a 10-point halftime deficit to beat the San Francisco 49ers 20-17.

Kyler Murray scored five touchdowns and linebacker Chandler Jones had a career-high five sacks as the Arizona Cardinals simply dominated the Tennessee Titans 38-13 for a big road win to open the season.

Benny Snell Jr. added a 1-yard TD run, and Ray-Ray McCloud set up a touchdown with a 57-yard punt return. Pittsburgh scored at least 26 points for a sixth straight game to tie a stretch in 2015 for the longest in franchise history. Pittsburgh dominated early with a 161-1 edge in total offense before the Titans' second offensive possession. Roethlisberger and the Steelers scored a touchdown on their opening drive for the first time in 23 games, going 75 yards over 16 plays. UP NEXTSteelers: Visit Baltimore in a game rescheduled because of the Titans' outbreak with the Ravens coming off their bye.