The NFL’s new year officially kicked off Wednesday, two days after teams began spending big money in free agency.

Star running back Saquon Barkley was listed as questionable for the New York Giants game against the Dolphins in Miami on Sunday.

Christian McCaffrey scored a touchdown in his 12th straight game, Brock Purdy threw two TD passes and the San Francisco 49ers won their 13th straight regular season game, 30-12 over the New York Giants.

Two Giants defenders tackled Jacksonville’s Christian Kirk inside the 1-yard line as time expired, preserving New York’s 23-17 victory over the Jaguars to match its best start since 2008.

New York Giants rookie tight end Daniel Bellinger was taken to a hospital with a bloody eye injury during a game Sunday at Jacksonville.

Daniel Jones is looking to stay undefeated in his career against Washington when he leads the New York Giants into the NFC East matchup on Thursday night.

(AP Photo/John Froschauer)Denver Broncos running back Phillip Lindsay has cleared concussion protocol and will play against the Los Angeles Chargers. Bears: WR Ted Ginn Jr., DB Duke Shelley, RB Artavis Pierce, OL Cody Whitehair, WR Riley Ridley, LB Trevis Gipson. Seahawks: RB Chris Carson, RB Carlos Hyde, DE Benson Mayowa, CB Ugo Amadi, SS Jamal Adams, CB Shaquill Griffin. ___LOS ANGELES RAMS AT MIAMIRams: RB Raymond Calais, OL Brian Allen, WR Trishton Jackson, TE Brycen Hopkins, DL A’Shawn Robinson. Dolphins: RB/WR Lynn Bowden Jr., RB Salvon Ahmed, FB Chandler Cox, CB Jamal Perry, RB Jordan Howard, DE Jason Strowbridge.

___GREEN BAY AT TAMPA BAYPackers: RB Tyler Ervin, CB Kevin King, QB Jordan Love. ___NEW YORK JETS AT MIAMIJets: QB James Morgan, QB Sam Darnold, CB Quincy Wilson, LB Jordan Willis, T Mekhi Becton, DL Nathan Shepherd. Dolphins: B/WR Malcolm Perry, RB Salvon Ahmed, RB Jordan Howard, LB Kyle Van Noy, DE Jason Strowbridge. ___HOUSTON AT TENNESSEETexans: WR Keke Coutee, CB Cornell Armstrong, RB Buddy Howell, ILB Peter Kalambayi, OT Charlie Heck, TE Jordan Akins. ___ATLANTA AT MINNESOTAFalcons: CB Jordan Miller, RB Qadree Ollison, S Jaylinn Hawkins, RT John Wetzel, DE Takk McKinley.