Christian McCaffrey ran for the go-ahead touchdown with 7:54 to play, and the San Francisco 49ers beat the Los Angeles Chargers 22-16 in their first game back from a bye week.

Quarterback Justin Herbert is expected to start for the Los Angeles Chargers on Sunday against the Jacksonville Jaguars after being questionable all week due to a rib injury.

Third-string quarterback Bryce Perkins threw a pair of touchdown passes to Lance McCutcheon and the Los Angeles Rams held off the Los Angeles Chargers 29-22 in a preseason game in which most of the starters for both teams did not play.

Trey Lance threw two touchdown passes and continued to make his case to be San Francisco’s Week 1 starter as the 49ers rallied for a 15-10 victory over the Los Angeles Chargers.

Darius Bradwell rushed for a touchdown in the third quarter and the Los Angeles Chargers beat the Los Angeles Rams 13-6 Saturday night in the first NFL game with fans at SoFi Stadium.

Tampa Bay Buccaneers quarterback Tom Brady (12) throws during the first half of an NFL football game against the Detroit Lions, Saturday, Dec. 26, 2020, in Detroit. The Bucs (10-5) set a franchise record with 588 yards and snapped the NFL’s second-longest postseason drought behind Cleveland’s 18-year run that can end Sunday. RECORD WATCHBrady has thrown a franchise-record 36 touchdowns and set a personal record with 348 yards passing by halftime. Tampa Bay set team records in points (34) and yards (410) in the first half. Lions: Stafford left the game with an ankle injury after he was 2 of 3 for 17 yards on his only possession.

Green Bay Packers quarterback Aaron Rodgers throws during the first half of an NFL football game against the Detroit Lions, Sunday, Dec. 13, 2020, in Detroit. Rodgers ran for a tiebreaking score in the third quarter and threw three touchdown passes, lifting the Green Bay Packers to a 31-24 win over the the Detroit Lions to clinch the NFC North title. “To have the whole thing come through Green Bay is something we’ve talked about for a long time," Rodgers said. “That would definitely be in our favor with the weather that we have in Green Bay. Green Bay repeated as division champion with its win and Minnesota’s loss to Tampa Bay earlier in the day.

DETROIT – Detroit Lions quarterback Matthew Stafford was placed on the Reserve/COVID-19 list, although his wife Kelly said on social media he tested negative. The Reserve/COVID-19 list was created for players who either test positive or have been in close contact with an infected person. Some NFL teams have closed their training centers after players and or staff members tested positive for COVID-19. Three months ago, the Lions removed Stafford from the COVID-19 list after saying he received a false positive test result. Kelly Stafford had plenty to say on her Instagram page in August after the false positive test, lashing out at the league for publicly putting her husband on the list.