Falling behind by a double-digit deficit is typically a death knell for most NFL teams.

Javonte Williams rushed for two touchdowns and the Denver Broncos triumphed in coach Sean Payton’s return to New Orleans, beating the banged-up and reeling Saints 33-10.

Tom Brady stayed undefeated abroad by throwing two touchdown passes to help the Tampa Bay Buccaneers beat the Seattle Seahawks 21-16 in the first regular-season game played in Germany.

Wilson and Metcalf tormented San Francisco and its banged up secondary as the top-scoring offense in the league continued to pile up points. Wilson found rookie DeeJay Dallas on a 2-yard TD pass after San Francisco went three-and-out to open the second half for a 20-7 lead. The momentum from two straight wins for San Francisco (4-4) evaporated in a hurry as more injuries continued to pile up. On Metcalf’s second TD, Moseley was flagged for interference but couldn’t keep Metcalf’s size and strength from still making the catch. San Francisco played without starters Deebo Samuel, Jeff Wilson Jr., Kwon Alexander and safety Jaquiski Tartt.