Bryce Harper and the Philadelphia Phillies are set to play the Houston Astros in the World Series.

Tony La Russa stepped down as manager of the Chicago White Sox because of a pair of health issues.

Tony La Russa moved into sole possession of second on baseball’s career manager wins list, snapping a tie with John McGraw by directing the Chicago White Sox to a 3-0 victory over the Detroit Tigers.

Rookie Yermín Mercedes hit a game-ending single, Yasmani Grandal homered twice and the Chicago White Sox beat the Detroit Tigers 9-8.

Hall of Famer manager Tony La Russa's second stint with the Chicago White Sox is off to a bumpy start.

EARLY TESTSThe Washington Nationals will be short-handed due to a positive coronavirus test for the second straight season opener. General manager Mike Rizzo did not reveal who the five players were, and the only certainty as of Wednesday night was that opening day starter Max Scherzer wasn't one of them. The Nationals did not have any players test positive during spring training prior to that. But in a what-are-the-odds moment, all three are set to start on opening day. To be pitching the same day as those guys is pretty cool.”MITTS AND MITTENSNolan Arenado, Kris Bryant and Miguel Cabrera will be wearing gloves on opening day.

All 30 teams are scheduled to be in action, with Gerrit Cole set to throw the first pitch of the season against Toronto at Yankee Stadium. A year after no fans were allowed during the virus-shortened 60-game season, every stadium is open, in varying degrees as teams adhere to coronavirus protocols. But in a what-are-the-odds moment, all three are set to start on opening day. To be pitching the same day as those guys is pretty cool.”AdMITTS AND MITTENSNolan Arenado, Kris Bryant and Miguel Cabrera will be wearing gloves on opening day. Rain is in the forecast along the East Coast, which could affect games at Fenway Park, Yankee Stadium, Citizens Bank Park and Nationals Park.

File-This Jan. 28, 2020, file photo shows a remembrance board at a memorial for Kobe Bryant near Staples Center in Los Angeles. LeBron, on court, gives heartfelt shout,A declaration: “Mamba out.”Sports still reeling by Super Bowl,Where Patrick Mahomes takes control. Defying odds, even reason,Baseball makes it through its season,Leaving summer and into fall --Bob Gibson ’s time, October ball. Through it all, a truth emerges:Games go on while COVID surgesAnd records fall, that much is clear --Consider Tara VanDerveer. But we’ll toast, of course, don’t think twice --Take a deep breath and roll the dice.

FILE - Former Philadelphia Phillies' Dick Allen waves to the crowd before a baseball game against the New York Mets in Philadelphia, in this Saturday, Aug. 12, 2017, file photo. Dick Allen, a fearsome hitter who was a seven-time All-Star, the 1964 NL Rookie of the Year and the 1972 AL MVP, has died. “My friends, these (negative) labels have kept Dick Allen out of the Hall of Fame,” Schmidt said. After seven years in Philadelphia, Allen played a season each with the Cardinals and Dodgers. To me, it was typical Dick Allen: I’ve had enough.

White Sox spokesman Scott Reifert said Monday the team was aware of the arrest when the 76-year-old La Russa was hired late last month. The 76-year-old La Russa is the oldest manager in the major leagues by five years. La Russa is 2,728-2,365 with six pennants over 33 seasons with the White Sox, Oakland and St. Louis. La Russa and Sparky Anderson are the only managers to win the World Series in the American League and National League. La Russa, who is friends with chairman Jerry Reinsdorf, started his managing career with the White Sox during the 1979 season.

FILE - In this Aug. 30, 2014, file photo, former Chicago White Sox manager Tony La Russa stands with his Baseball Hall of Fame plaque before the second baseball game of a doubleheader against the Detroit Tigers in Chicago. The 76-year-old La Russa rejoins the franchise where his managing career began more than four decades ago. He takes over for Rick Renteria after what the White Sox insisted was a mutual agreement to split. Though he hasn’t been in a dugout in nine years, La Russa has remained a part of the game. Now, the White Sox are banking on La Russa to help push them to championships, just as he did with Oakland and St. Louis.

CHICAGO – The Los Angeles Angels granted the Chicago White Sox permission to interview Hall of Famer Tony La Russa for their managing job, a person familiar with the situation said Wednesday. A three-time World Series-winning manager, the 76-year-old La Russa joined the Angels prior to this season as senior advisor of baseball operations. La Russa, who started his managing career with the White Sox during the 1979 season, hasn't managed since 2011, when he led St. Louis past Texas in the World Series. Chairman Jerry Reinsdorf has long regretted that move and remains close with La Russa. If La Russa gets the job, he will inherit a team that appears poised for long-term success.